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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
54 Results for "
Rheum australe D. Don
" in MedChemExpress (MCE) Product Catalog:
Products (54)
54 Results for "Rheum australe D. Don" in MCE Product Catalog:
17
17 Cited Publications
Synonyms: L-6-Diazo-5-oxonorleucine; Don
6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity .
9
9 Cited Publications
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JHU-083, a proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b + cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals .
Category:
Other Diseases Campanulaceae Codonopsis pilosula (Franch.) Nannf. Lipids Plants Disease Research Fields
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Cat. No.: HY-N11678
CAS No.: 131180-21-7
Synonyms: Don-3-β-D-glucoside; Deoxynivalenol 3-glucoside
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Cat. No.: HY-W099547
CAS No.: 2197-63-9
Cat. No.: HY-P991023
CAS No.: 2911590-72-0
Synonyms: 6MW3211
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Cat. No.: HY-N3706
CAS No.: 15297-92-4
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Cat. No.: HY-P11097
CAS No.: 3056822-31-9
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Cat. No.: HY-N6685
CAS No.: 50722-38-8
Synonyms: 3-AcDon; 3-ADon
Cat. No.: HY-179120
CAS No.: 3095661-21-2
ZJS178 is a novel inhibitor of myosin I. ZJS178 is a fungicide that has inhibitory activity against Fusarium graminearum and can reduce DON toxin synthesis. ZJS178 can be used for research on plant diseases such as wheat scab .
Cat. No.: HY-178717
CAS No.: 3057478-36-8
WML-01 is a fungicide with EC50s of 0.079, 0.72 and 2.02 μg/mL against F. graminearum, F. fujikuroi and S. sclerotiorum. WML-01 disrupts the cell membrane of F. graminearum and induces deposition of lipid droplets. WML-01 inhibits Deoxynivalenol (DON) (HY-N6684) biosynthesis with no cross-resistance and strongly suppresses ribosomal subunit assembly, impairing protein synthesis. WML-01 effectively controls the fusarium head blight (FHB) epidemic .
Cat. No.: HY-108357R
CAS No.: 157-03-9
Synonyms: L-6-Diazo-5-oxonorleucine (Standard); Don (Standard)
6-Diazo-5-oxo-L-nor-Leucine (Standard) is the analytical standard of 6-Diazo-5-oxo-L-nor-Leucine. This product is intended for research and analytical applications. 6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity[1][2][3].
Category:
Natural Products Other Diseases Campanulaceae Codonopsis pilosula (Franch.) Nannf. Plants Disease Research Fields
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Cat. No.: HY-153151
CAS No.: 1998724-98-3
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Fmoc-DON-Boc (Compound 8b) is an Fmoc-protected compound that can be used for the synthesis of proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357). DON is a glutamine antagonist .
Cat. No.: HY-N8129
CAS No.: 94356-23-7
Category:
Stilbenes Polygonaceae Other Diseases Rheum rhabarbarum Linnaeus Phenols Polyphenols Plants Disease Research Fields
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Cat. No.: HY-N12783
CAS No.: 40950-57-0
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Cat. No.: HY-N15727
CAS No.: 1251459-63-8
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Cat. No.: HY-N11790
CAS No.: 64898-03-9
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
